![]() ![]() This often necessitates a midday dose at school, which can be embarrassing to a child. ![]() The use of medications to treat ADHD has greatly increased, yet the dosage requirements for many children differ from strengths that are commercially available. Topical spironolactone reduces sebum secretion rates in young adults.ĭepartment of Dermatology, Niigata University School of Medicine, Japan.Ĭlick here to access the PubMed abstract of this article. Shalita AR, Smith JG, Parish LC, Sofman MS, Chalker DKĭepartment of Dermatology, State University of New York, College of Medicine, Brooklyn, USA.Ĭlick here to access the PubMed abstract of this article. Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. We can compound cosmetically-appealing customized formulations which can contain numerous medications to provide a synergistic effect for treatment of resistant acne. AcneĮmergence of resistant pathogens emphasizes the need for alternatives to antimicrobial agents for acne therapy. The efficacy of any compounded medication is influenced by the technique and equipment used in preparing the formulation, the purity and quality of the ingredients, choice of vehicle (base), and proper use of additives such as penetration enhancers. We must consider physical and chemical properties of each active and inactive ingredient in order to prepare an effective and safe customized medication with the desired taste, color, fragrance, viscosity, uniformity, texture, and stability. Professional compounding is not just diluting existing medications, or mixing powders with bases. Most drugs can be compounded into transdermal gels that can easily be applied to an appropriate site, such as the child's wrist, for absorption through the skin. Lollipops are an ideal alternative to "swish and swallow" medications that need to be retained in the mouth for a prolonged period of time. A palatable formulation is more likely to improve compliance and minimize spillage or waste during administration. We can compound oral medications into pleasantly flavored suspensions, solutions, concentrates, freezerpops, "gummy bears" or lozenges, in colors that entice the child to take the medication. Fortunately, our compounding pharmacy is able to help. Most medications are not labeled for pediatric populations, and when a medication is not approved for use in infants and children, it usually is not available in a suitable pediatric dosage form. The limited pediatric market for most drugs may be the leading reason for the lack of investment in drug development for this population by the pharmaceutical industry. We work together with prescribers, children, and their families to customize medications and meet specific needs.Ĭhildren pose many challenges when it comes to medication: they may resist having to take a medication, dislike the taste or texture, have difficulty swallowing solid dosage forms, and are fearful of injections.
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